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A new era of PGS for IVF - will it yield the anticipated improved efficiency?
Author(s): Simon Fishel, Simon Thornton and Ken DowellSimon Fishel, Simon Thornton and Ken Dowell
At the outset it is necessary to establish the acronyms that geographically have a different meaning. In the UK and elsewhere it is customary to separate out the screening of chromosomes (Preimplantation Genetic Screening - PGS) from diagnosing a single gene disorder - Preimplantation Genetic Diagnosis (PGD). In some regions, notably the US, both processes PGS and PGD are often included in the over-arching term, PGD. This short article deals only with PGS (perhaps better described as Chromosome Screening). However, it should be noted that with some platforms it is becoming increasingly easier to deliver information on not only the full complement of chromosome information, including a translocation, but also the diagnosis of a monogenic diseased state as well as HLA matching, from a single cell  - an exciting prospect indeed. .. View More»