Andrology-Open Access
Open Access
ISSN: 2167-0250
+44 1300 500008
ISSN: 2167-0250
+44 1300 500008
Silvia Zago
Italy
Research Article
Testicular Microlithiasis and Testicular Germ Cell Tumors: A Seven Year Retrospective Study
Author(s): Gian Carlo Parenti, Ugo De Giorgi, Elisa Gaddoni, Vincenza Conteduca, Silvia Zago, Paolo Campioni, Melchiore Giganti and Fabrizio AlbarelloGian Carlo Parenti, Ugo De Giorgi, Elisa Gaddoni, Vincenza Conteduca, Silvia Zago, Paolo Campioni, Melchiore Giganti and Fabrizio Albarello
Purpose: To evaluate the association between grade II and III testicular Microlithiasis (TM) and Testicular Germ Cell Tumor (TGCT), reporting disease-free survival over 7 years.
Materials and Methods: The association between TM and TGCT was studied in 7,320 male patients referred to the radiology department of an Italian hospital for several scrotal disease. TM associated with TCGT was diagnosed in all men by ultrasound (US) and by testicular histology specimens. All patients with TM were followed-up annually with US. Chi-square, Kaplan-Meyer and Fisher’s exact test were used for statistical analysis.
Results: The incidence of TM was 1.4% (98 of 7320). Twenty eight patients with TGCT (28 of 58, 48.2%) had associated TM. During the follow-up, testicular cancer was detected in six patients (incidence 6.12%, 95% confidence interval from 2.8 to 12.7); four of the.. View More»
DOI:
10.4172/2167-0250.1000115