ISSN: 2155-9880
+44 1300 500008
Sean Hennessy
Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania,
Philadelphia, Pennsylvania, USA
Hennessy’s primary field of interest is pharmacoepidemiology, which is the study of the health effects of drugs and other medical products in populations. He co-led a pair of studies demonstrating the effectiveness and safety of the SA14-14-2 vaccine for Japanese encephalitis that has since led to the immunization of millions of children per year in countries including North and South Korea, Nepal, India, Cambodia and Sri Lanka. He also evaluated an early approach to using medical insurance data to improve prescribing, finding it ineffective despite its federal mandate. This contributed to the omission of drug utilization review programs from Medicare Part D. His research has produced crucial knowledge about the cardiovascular safety of many widely-used drugs for mental health conditions in including ADHD, depression, and schizophrenia. He has identified a survival benefit of potassium supplementation in diuretic users and studied serious health consequences of drug-drug interactions involving high-risk drugs including anticoagulants, antidiabetic agents and antiplatelet agents. He also collaborates on studies aimed at improving pharmacoepidemiology research methods.