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Sawsan K El-Sayed
Influence of Male Personal and Demographic Characteristics on Semen Parameters and Intracytoplasmic Sperm Injection Outcome; Is Sperm DNA Integrity Testing Clinically Relevant?
Author(s): Sawsan K El-Sayed, Naglaa A Ahmed, Mohamed I Aref and Ahmed F El-SherbinySawsan K El-Sayed, Naglaa A Ahmed, Mohamed I Aref and Ahmed F El-Sherbiny
The aim of the present study was to evaluate the impact of male characteristics on semen quality and to evaluate the impact of items of both parameters on ICSI outcome, with special focus on the clinical significance of sperm DNA integrity testing. Patients and Methods: This study included 100 non-azoospermic infertile men scheduled for ICSI. For each patient, full personal, demographic and medical data were collected and its relation to standard semen parameters, sperm DNA fragmentation (assessed by COMET assay) and ICSI outcomes were analysed. Results: Basic semen parameters were not correlated well with the studied male characteristics, except for the significant difference between hash users and non-users regarding seminal volume (p=0.019)... View More»