Journal of Applied Pharmacy
Open Access

Saeed A Qureshi

Publications

• Review Article
  A Critical Assessment of Current Practices of Drug Dissolution Testing Irrelevancies, their Causes and Suggestions to Address These
  Author(s): Saeed A QureshiSaeed A Qureshi
  
  In principle, drug dissolution testing should be one of the simplest analytical techniques, however, in practice it is perhaps the most confusing, complex and frustrating techniques often lacking scientific and/or logical considerations. Perhaps the strange aspect of current practices is that despite the availability of hundreds, if not thousands, of methods and numerous regulatory guidance, if given a blinded sample of a simple tablet or capsule product one cannot determine its dissolution characteristics. On the other hand, fortunately, if one applies common and well established scientific principles and logical judgements, drug dissolution testing can become a powerful analytical tool based on a simple set of experimental conditions. The purpose of this article is to highlight some of the critical irrelevancies of current practices. Describing basic principles of underlying science.. View More»
  DOI: 10.4172/1920-4159.1000208

  Abstract PDF

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