Clinical & Experimental Cardiology

Clinical & Experimental Cardiology
Open Access

ISSN: 2155-9880

Pietro Delise

Pietro Delise
Clinica Pederzoli,
Peschiera, Verona

  • Short Communication
    Brugada Syndrome 26 Years Later: More Questions than Answers
    Author(s): Pietro Delise, Giuseppe Allocca and Nadir SittaPietro Delise, Giuseppe Allocca and Nadir Sitta

    Brugada Syndrome and Brugada type 1 ECG pattern (BrS type 1 ECG) are currently used as synonyms. However, in the vast majority of cases, BrS type 1 ECG is a benign finding, and only few patients with this pattern have a Brugada Syndrome; that is to say, they present with, or are prone to, malignant arrhythmias. Brugada Syndrome, when defined only on the basis of the BrS type 1 ECG, has several characteristics which conflict with those of other channellopathies such as Long-QT syndrome (LQTS). For example, there is no correlation between the magnitude of ECG anomalies and prognosis, and a genetic defect is rarely recognized. In addition, patients with malignant arrhythmias in prospective and retrospective studies have different characteristics. Indeed, prospective studies have identified a number of risk factors which are useful (singly or in combination) in identifying patient.. View More»

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