Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biol
Open Access
ISSN: 2375-4508
+44 1478 350008
ISSN: 2375-4508
+44 1478 350008
Paul Brezina
Assistant Clinical Professor of Reproductive Endocrinology and Infertility, Vanderbilt University School of Medicine,
Tanzania
Research Article
Sibling Oocytes Randomly Assigned to Either Conventional Fertilization or Intracytoplasmic Sperm Injection Demonstrate Equivalent Fertilization and Blastulation Rates
Author(s): Kyle J Tobler, Paul Brezina, Jairo E Garcia and Yulian ZhaoKyle J Tobler, Paul Brezina, Jairo E Garcia and Yulian Zhao
Background: To determine the difference in fertilization and blastulation rates between sibling oocytes randomly assigned to either Conventional Fertilization (CF) or Intracytoplasmic Sperm Injection (ICSI) in patient couples with normal semen analysis parameters.
Methods: A retrospective review of embryologic and clinical outcomes from patients undergoing their first In Vitro Fertilization (IVF) cycle that randomly assigned one-half of sibling oocytes to either CF or ICSI. Randomization occurred prior to removal of the oocyte cumulus cells which allows identification of metaphase II oocytes eligible for ICSI. All male partners met normal semen analysis parameters and normal fertilization was anticipated for the IVF cycle. Each patient served as their own control.
Results: A total of 682 oocytes were included and were assigned to either CF or ICSI. The CF had a significa.. View More»
DOI:
10.4172/jfiv.1000124