Organic Chemistry: Current Research
Open Access
ISSN: 2161-0401
ISSN: 2161-0401
Norma Flores-Holguin
Miguel de Cervantes 120, Complejo Industrial Chihuahua, Chihuahua 31190
Mexico
Research Article
DFT Chemical Reactivity Analysis of Biological Molecules in the Presence of Silver Ion
Author(s): Linda-Lucila Landeros-Martinez, Erasmo Orrantia-Borunda and Norma Flores-HolguinLinda-Lucila Landeros-Martinez, Erasmo Orrantia-Borunda and Norma Flores-Holguin
Silver ion oxidation process was studied in different biological molecules by Density Functional Theory; this by using the Becke three parameter Lee, Yang, and Parr functional and the Pople 6-31G (d) and Los Alamos LANL2DZ basis sets. The calculation was used to find the lowest energy molecular structure, molecular orbitals, and chemical reactivity parameters. Chemical hardness showed that the oxidation process begins in the purine and pyrimidine bases. The frontier orbitals electronic density distribution were analyzed in the biological molecule-silver ion complex. This distribution clearly revealed the transfer of electrons from highest occupied molecular orbital to lowest unoccupied molecular orbital indicating an oxidation process.
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DOI:
10.4172/2161-0401.1000153