Medical & Surgical Urology

Medical & Surgical Urology
Open Access

ISSN: 2168-9857

Mohamed Yehia

Mohamed Yehia
Wrexham Maelor Hospital,
United Kingdom

  • Research Article
    Predicting the Immune Response Following Intravesical BCG; is it Possible?
    Author(s): Mohamed Yehia and Omar ElgebalyMohamed Yehia and Omar Elgebaly

    Objective: To demonstrate and quantify the immune response changes over time in patients with Non-muscleinvasive Bladder Cancer (NMIBC) treated with bacillus Calmette-Guerin (BCG).Methods: The study enrolled 52 patients. Group A included 32 patients with high risk and intermediate risk NMIBC treated with TURBT and intravesical BCG. Group B included 20 patients underwent cystoscopy for other indications. Monitoring immune changes was done by quantifying the percentage of T lymphocytes in urine samples taken before BCG therapy, immediately after BCG therapy and 3 months later. Patients in Group A were followed for 1 year and the clinical outcome was correlated to the level of the immune response.Results: In the initial urine samples taken before BCG therapy the mean flowcytometeric percentages of the T lymphocytes were compa.. View More»
    DOI: 10.4172/2168-9857.1000213

    Abstract PDF

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