Clinical & Experimental Cardiology
Open Access

Min Yu

Publications

• Research Article
  Liquiritigenin Enhances the Radiosensitivity of Nasopharyngeal Carcinoma Cell by Affecting Its Autophagy
  Author(s): Ke Yang, Yujie Li, Min Yu and Xu SunKe Yang, Yujie Li, Min Yu and Xu Sun
  
  Objective: To investigate the effect of licorice on radiosensitization of nasopharyngeal carcinoma cells and its mechanism. Methods: MTT assay was used to detect the effect of different concentrations of glycyrrhizin on the activity of nasopharyngeal carcinoma cells. The changes of autophagy were observed by transmission electron microscopy (TEM) in the treatment of nasopharyngeal carcinoma cells. Western blotting was used to detect the effect of glycyrrhizin on the level of autophagy protein in nasopharyngeal carcinoma. Flow cytometry was used to detect the changes of apoptosis rate of nasopharyngeal carcinoma cell line after radiotherapy. Results: After successfully constructing CNE-2-RR radiation resistant cell line, MTT assay was used to detect the best inhibition rate of 20 mmol/L glycyrrhizin on nasopharyngea.. View More»
  DOI: 10.4172/2155-9880.1000561

  Abstract PDF

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