Journal of Depression and Anxiety
Open Access
ISSN: 2167-1044
+44 1223 790975
ISSN: 2167-1044
+44 1223 790975
Michael Ertl
Klinikum Augsburg Hospital,
Augsburg
Germany
Research Article
Influence of Positive End-Expiratory Pressure Ventilation on Cerebral Perfusion and Cardiac Hemodynamics
Author(s): Roland Backhaus, Elisabeth Torka, Michael Ertl, Lukas Kirzinger, Andrea Wagner, Dobri Baldaranov, Felix Schlachetzki and Kornelius FuchsRoland Backhaus, Elisabeth Torka, Michael Ertl, Lukas Kirzinger, Andrea Wagner, Dobri Baldaranov, Felix Schlachetzki and Kornelius Fuchs
Objective: Positive end-expiratory pressure (PEEP) ventilation is used to prevent alveolar collapse and improve oxygenation. PEEP ventilation hinders venous backflow to the right atrium as well as venous outflow from the brain including the spinal cord. This may have an effect on cardiac output (CO) and could result in an elevation in intracranial pressure (ICP) — an important cause of secondary brain injury. The aim of this study was to investigate the effect of moderate changes in PEEP values on hemodynamics and cerebral perfusion in neurological patients experiencing respiratory failure.
Methods: The study focused on 7 patients in a neurological intensive care unit who suffered from respiratory failure. Cerebral blood flow velocity was measured using transcranial color-coded duplex sonography (TCCS) while moderate changes in PEEP le.. View More»
DOI:
10.4172/2167-1044.1000285