Journal of Clinical and Cellular Immunology

Journal of Clinical and Cellular Immunology
Open Access

ISSN: 2155-9899

+44 1223 790975

Mark Aragones

Mark Aragones

Philippines

Publications
  • Review Article
    The Role of B Cells in Autoimmunity: Insights on B Lymphocyte Stimulation (Blys) as a Target for Biologics in Systemic Lupus Erythematosus
    Author(s): Evan S Vista and Mark AragonesEvan S Vista and Mark Aragones

    Systemic lupus erythematosus (SLE) is a heterogenous condition with significant impact on morbidity and mortality among affected individuals, usually young females during their most productive stage in life. The production of pathogenic autoantibodies has been the classical hallmark for the disease. B cells, the precursor of the antibody producing plasma cells, are believed to play a central role in SLE disease activity. It has long been considered a difficult disease to manage and diagnose due to its wide raging manifestations and severity. This systemic autoimmune condition has attracted many clinicians and researchers for decades in the hope of fully unraveling the disease pathogenesis in order to come up with more effective treatments. Treatment strategies have been broadly directed at dampening the immune response with consequential adverse effects in the long term care of diseas.. View More»
    DOI: 10.4172/2155-9899.1000360

    Abstract PDF

Relevant Topics

Top