Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biol
Open Access
ISSN: 2375-4508
+44 1478 350008
ISSN: 2375-4508
+44 1478 350008
Marina Ferrario
Reproductive Medicine Unit,
Ospedale Papa Giovanni XXIII, Piazza OMS 1, 24127 Bergamo
Italy
Short Communication
The Use of Corifollitropin Alfa in Combination with a GnRH Analogue as Final Trigger in the Potential High Responders
Author(s): Francesco M. Fusi, Mariangela Arnoldi, Rita Secomandi, Laura Zanga, Alessia Galimberti, Enrica Capitanio and Marina FerrarioFrancesco M. Fusi, Mariangela Arnoldi, Rita Secomandi, Laura Zanga, Alessia Galimberti, Enrica Capitanio and Marina Ferrario
Background: A great concern exists in using corifollitropin alfa to induce ovarian stimulation in high responders due to the riskof OHSS.In this study, we utilized corifollitropin alfa in patients with the potential of being high responders, in addition to the GnRH analog triptorelin, as final trigger to induce the oocyte maturation. Intensive luteal support was administered to allow the transfer in the same cycle.
Patients and methods: Between January 2013 and September 2014, 35 patients were stimulated with corifollitropin alfa and underwent in vitro fertilization or intracytoplasmic sperm injection procedures. All women had levels of antimullerian hormone>3 ng/ml and antral follicle count >10 and <20. The patients with polycystic ovarian syndrome were excluded from the study.
Results: The mean number of.. View More»
DOI:
10.4172/2375-4508.1000143