Organic Chemistry: Current Research
Open Access
ISSN: 2161-0401
+44 1478 350008
ISSN: 2161-0401
+44 1478 350008
Manojkumar U Chopade
Pune-411 007, Maharashtra
India
Research Article
Enantioselective Michael Addition of Diethyl Malonate on Substituted Chalcone Catalysed by Nickel-Sparteine Complex
Author(s): Manojkumar U ChopadeManojkumar U Chopade
A series of transition metal with Sparteine a novel chiral catalyst was facilely synthesized, all of which contain a chiral Sparteine unit as a bidentate ligand. These bidentate chiral auxiliaries were found to be an efficient chiral catalyst in nickel-mediated, enantioselective Michael addition of Diethyl malonate to substituted chalcone. The corresponding adducts were obtained in good yields (80-91%) under simple and clean reaction condition.
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DOI:
10.4172/2161-0401.1000178