Journal of Clinical and Cellular Immunology

Journal of Clinical and Cellular Immunology
Open Access

ISSN: 2155-9899

Manal Mohamed Saber

Manal Mohamed Saber
Faculty of Medicine,

  • Research Article
    The Use of the Cytokines EMAP-II, IL-19 and IL-10 as Biomarkers to Determine Prognosis of Non – Hodgkin’s Lymphoma
    Author(s): Manal Mohamed SaberManal Mohamed Saber

    Objectives: Establishing diagnostic and prognostic factors are very important in the management of Non-Hodgkin Lymphoma (NHL). Our aim was to evaluate the clinical significance of serum EMAP-II, IL-19, and IL–10 in NHL patients for assessing treatment response and prognosis of patients. Methods: Serum EMAP-II, IL-19, and IL-10 levels were measured in the serum of 64 NHL patients before and after treatment with CHOP-based chemotherapy by enzyme-linked immunosorbent assay. Correlations of marker levels to the laboratory, clinicopathological and immunophenotyping markers were performed. Results: Serum levels of EMAP-II and IL-10 were higher before therapy and decreased significantly thereafter (P<0.001). High EMAP-II and IL-10 were correlated with serum ALT and blood urea respectively (P=0.043, P=0.020). Significan.. Read More»
    DOI: 10.4172/2155-9899.1000437

    Abstract PDF

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