Immunome Research

Immunome Research
Open Access

ISSN: 1745-7580

+44-77-2385-9429

Mahrous DM

Mahrous DM

Egypt

Publications
  • Research Article
    Comparison of the Immunity Status in-Between Children with β-Thalassaemia Major Receiving Different Treatment Modalities: A Single Egyptian District Study
    Author(s): Mahmoud SS, Mohamed GB, Hakeem GLA, Higazi AM, Nafady AAH, Farag NM, Mahrous DM, Kamal NN, Hassan Z, Aziz EA and Shaban A Mahmoud SS, Mohamed GB, Hakeem GLA, Higazi AM, Nafady AAH, Farag NM, Mahrous DM, Kamal NN, Hassan Z, Aziz EA and Shaban A

    Background: β-thalassaemia major is one of the chronic hemolytic anemias resulting from defect in β-globin chain. It requires frequent blood transfusion plus other treatment modalities. These treatment modalities may be associated with certain immunologic modulations. Objective: To assess the immunity status in children with β-thalassaemia major under different treatment regimens within El Minia, Egypt. Subjects and Methods: One hundred forty-four children were enrolled and classified into four groups. Thirty-six β-thalassaemia patients treated only with blood transfusion (group I). Thirty-six patients treated with transfusion and iron chelation (group II). Thirty-six patients treated with transfusion, iron chelation and subjected to splenectomy (group III). Group IV involved thirty-six apparent.. View More»
    DOI: 10.4172/1745-7580.10000127

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