ISSN: 2165-8048
Mahmoud Younis
Kafr Elshaikh General Hospital,
Egypt Ministry of Health
Egypt
Research Article
Growth Factors in Platelet Rich Plasma can Regenerate Pancreatic Beta Cells in Type 2 Diabetes
Author(s): Mahmoud YounisMahmoud Younis
Introduction: 387 million people are considered to have diabetes all over the world, and the number is expected to increase miserably to 592 million by 2035. Alternative ways to create β-cells from endogenous sources should be found as a way for the evolution of treatment. This is to bypass the complication of tissue matching and surgical procedures. To date several rebuilding approaches have been developed to stimulate β-cells regeneration through the induction of the proliferation of remaining β-cells, neo-genesis; de novo islet formation from pancreatic progenitor cells, and trans-differentiation; converting non-β-cells within the pancreas to β-cells. Platelet Rich Plasma (PRP) contains various growth factors which can be used for tissue regeneration including pancreatic beta cells.
Materials and methods:.. View More»
DOI:
10.35248/2165-8048.19.9.304