Journal of Clinical and Cellular Immunology

Journal of Clinical and Cellular Immunology
Open Access

ISSN: 2155-9899

+44 1223 790975

M. Rita I. Young

M. Rita I. Young
Strom Thurmond Research Building – 550,
114 Doughty St., Charleston, SC 29425

  • Review Article
    Th17 Cells in Protection from Tumor or Promotion of Tumor Progression
    Author(s): M. Rita I. YoungM. Rita I. Young

    The roles of inflammation and inflammatory cells such as Th17 cells in the development and progression of cancer have been extensively studied. However, the results have been varied, with conflicting conclusions. Most studies have focused on changes in inflammatory phenotypes once cancers have developed and disease is progressing. Far fewer studies have looked at the immune phenotypic changes that occur during progression of premalignant lesions to cancer. The impact of inflammation and, in particular, Th17 cells on tumor biology is summarized in this review, with a focus on the differences in the outcomes of studies. Possible explanations for the contradictory conclusions are also suggested. .. View More»
    DOI: 10.4172/2155-9899.1000431

    Abstract PDF

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