Journal of Thyroid Disorders & Therapy
Open Access
ISSN: 2167-7948
+44 1300 500008
ISSN: 2167-7948
+44 1300 500008
Libo Chen
Shanghai Jiao Tong University Affiliated Sixth People’s Hospital,
Shanghai 200233
Bolivarian Rep. of Venezuela
Research Article
Quantitative Radioiodine Treatment of Graves' Hyperthyroidism Using Different Intended Activities and the Same Weighting Factor
Author(s): Shiwei Sheng, Yang Wang, Maomei Ruan, Tao Ying and Libo ChenShiwei Sheng, Yang Wang, Maomei Ruan, Tao Ying and Libo Chen
Context: There is little consensus on the most appropriate dose regimen for radioiodine treatment (RIT) of Graves’ hyperthyroidism (GH), and quantitative studies on the role of the efficacy-affecting parameters are lacking.
Objective: This prospective study was designed to evaluate the feasibility of quantitative RIT of GH using a modified formula, which took into account eight parameters associated with the outcome.
Design: A 1-year follow-up study of 205 GH patients was performed.
The administered activity of 131I was established using a formula,
Activity MBq = [(gland weight (g) ×in tended activity) (MBq/g) /Max uptake] (% )× (1 + X/30) in which the X represented the sum of the parameters, and the administered activity increased or decreased by 1/30 when each of the parameters was prese.. View More»
DOI:
10.4172/2167-7948.1000157