ISSN: 2155-9880
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Research Article
Hemodynamics and Exercise Tolerance after Senning Operation for Transposition of Great Arteries and Its Limiting Factors: A Longitudinal Study
Author(s): Viktor Tomek, Jiri Radvansk, Theodor Adla, Vaclav Chaloupecky, Krystof Slaby, Jan Pokorny, Michal Prochazka, Petra Antonova and Jan JanousekViktor Tomek, Jiri Radvansk, Theodor Adla, Vaclav Chaloupecky, Krystof Slaby, Jan Pokorny, Michal Prochazka, Petra Antonova and Jan Janousek
Objectives: The purpose of this longitudinal study was to assess hemodynamics and exercise capacity in patients after Senning operation and to determine its limiting factors.
Methods: 87 long-term survivors of the Senning operation for transposition of great arteries were recruited for a longitudinal follow-up study consisting of two cross-sectional evaluations at a mean of 12.6 and 22.6 years after surgery, respectively. The protocol included a questionnaire, echocardiography, radionuclide angiocardiography, magnetic resonance imaging and cardiopulmonary exercise test. Decreased exercise capacity was defined as maximum oxygen uptake <-2 Z-scores.
Results: Hemodynamic variables (right ventricular function and degree of tricuspid regurgitation) and chronotropic competence did not change significantly with time. D.. View More»
DOI:
10.4172/2155-9880.1000437