Internal Medicine: Open Access
Open Access
ISSN: 2165-8048
ISSN: 2165-8048
Kamil Ashour Farhoud
Al- yarmouk Teaching Hospital,
Baghdad
Iraq
Research Article
Trastuzumab Related Cardio-toxicity in Breast Cancer Patients Single Center Experiences
Author(s): Kamil Ashour Farhoud and Eaman suud khalifaKamil Ashour Farhoud and Eaman suud khalifa
Background: Trastuzumab may induce cardio-toxicity which can be clinically identified as decreased left ventricular systolic function with or without symptoms of heart failure.
Objectives: To determine the prevalence and potential risk factors of trastuzumab related cardio-toxicity in breast cancer treated patients.
Methods: The study was carried out on 78 HER2- positive breast cancer patients who received trastuzumab in the Oncology Department of Al-yarmouk teaching hospital, Baghdad, between September, 2017 and April, 2018.
Results: Twenty two (28.2%) patients developed a significant declining in le ft ventricular systolic function (27.6% of early breast cancer patients and 29% of patients with metastatic disease). Seven of 78 patients (8.9%) developed symptomatic heart failure. Patients with tr.. View More»
DOI:
10.4172/2165-8048.1000275