Journal of Nanomedicine & Biotherapeutic Discovery

Journal of Nanomedicine & Biotherapeutic Discovery
Open Access

ISSN: 2155-983X

K Sujatha

K Sujatha

Porur, Chennai

  • Research Article
    Development, Characterization and Antidiabetic Potentials of Nilgirianthusciliatus Nees Derived Nanoparticles
    Author(s): K Kavitha, K Sujatha and S ManoharanK Kavitha, K Sujatha and S Manoharan

    Nilgirianthus ciliatus Nees is used in traditional Indian system of medicine for the treatment of numerous physiological disorders. Previous investigations revealed that various bioactive compounds have been isolated from this plant for the treatment of various disorders. But these compounds may be unstable in gastrointestinal tract due to the elevated pH and harsh condition that renders the bioactive compounds ineffective. In order to improve the pharmacokinetic and pharmacodynamic properties of various drugs, nanoparticles were developed by various techniques. Nanoformulation of ethanolic extract of Nilgirianthus ciliatus was prepared by solvent evaporation technique using gelatin as carriers and evaluated its antidiabetic effects in L6 myoblasts and 3T3L1 adipocytes. The mean particle size of plant extract loaded gelatin nanoparticles was approximately 110 nm and .. Read More»
    DOI: 10.4172/2155-983X.1000152

    Abstract PDF

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