Clinical & Experimental Cardiology
Open Access
ISSN: 2155-9880
ISSN: 2155-9880
Jitka Virag
Assistant Professor
She is an Assistant Professor in Brody School of Medicine from East Carolina State University. Her research interests reflect in her wide range of publications in various national and international journals. Her research interests reflect in her wide range of publications in various national and international journals
Heart failure is a significant public health problem. Since the heart lacks sufficient regenerative potential to recover from an ischemic event, efforts are being made to prevent excessive damage and alleviate subsequent remodeling and heart failure through the use of gene or protein therapy alone or in conjunction with cell/tissue grafting. We employ the murine model of myocardial infarction, to study acute ischemia/reperfusion injury as well as chronic remodeling in non-reperfused myocardial infarction. This is a very valuable tool that can be used to investigate factors that mediate injury, determinants of the extent of remodeling, and interventions that can impede or even halt these processes once they have begun.