Journal of Molecular Imaging & Dynamics
Open Access

Hongyan Du

Publications

• Research Article
  Would Sub-regional Analysis Improve Sensitivity in Knee dGEMRIC?
  Author(s): Wei Li, Hongyan Du and Pottumarthi V. PrasadWei Li, Hongyan Du and Pottumarthi V. Prasad
  
  Purpose: To evaluate if sub-regional analysis could offer higher sensitivity than full-thickness analysis when quantifying dGEMRIC data of the knee. Materials and methods: A dGEMRIC data set of medial femoral cartilage of the knee, including thirteen patients with osteoarthritis (diseased) and fourteen asymptomatic subjects (control), was reanalyzed with sub-regional analysis, i.e. using two ROIs (regions of interest) representing superficial region and deep region of the cartilage respectively, in addition to full-thickness ROI. Comparisons were made in T1pre (spin-lattice relaxation time without contrast administration), T1Gd (after Gd-DTPA2- administration), and ΔR1 (the change of relaxation rate) obtained with the three analysis methods. Results: Differences between superficial region and deep region in T.. View More»
  DOI: 10.4172/2155-9937.1000105

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