Clinical & Experimental Cardiology
Open Access
ISSN: 2155-9880
ISSN: 2155-9880
Hai bin Yu
Indiana
Research Article
Myocardial Protective Effect of Exogenous Creatine Phosphate in Children Undergoing Open Heart Surgery
Author(s): Khan Mohammed Firoj, Hai bin Yu and Xian en FaKhan Mohammed Firoj, Hai bin Yu and Xian en Fa
Objective: To explore the protective role of exogenous Creatine Phosphate (PCr) in the postoperative cardiac muscle recovery in children undergoing open heart surgery.
Material and methods: 63 cases of congenital heart disease were randomly divided into 3 groups; A, B and C; 21 cases in each group. Myocardial perfusion fluids were made of the same amount of blood in the St, Thomas Hospital cardioplegic solution type 2 (STH 2). In B and C group, intraoperative myocardial perfusion solution added with exogenous CP. All the groups were postoperatively treated with general fluid therapy, while group C was given postoperative intravenous exogenous CP. Trends of myocardial enzyme at different time points were monitored.
Results: At the end of surgery (T2), enzyme levels in the plasma were significantly increased, no difference.. View More»
DOI:
10.4172/2155-9880.1000450