University of Western Ontario, Canada
Grant McFadden is Professor of Microbiology and Immunology at the University of Western Ontario and the Robarts Research Institute in London, Ontario. He is one of the most prominent figures in his field of virology and his numerous scientific contributions have had a huge impact on fundamental understanding of the molecular biology of DNA viruses and on virus and host-cell interactions. The four areas of his most significant contributions might be summarized as: (1) The discovery and analysis of multiple classes of virus-encoded virokines and viroceptors, (2) The discovery of inhibitors of apoptosis encoded by poxviruses, (3) The analysis of poxvirus molecular biology and the basis for host tropism, and 4) The discovery of the novel anti-immune mechanism of poxviruses. Dr. MacFadden has received numerous awards including Canada Research Chair in Molecular Virology in 2001, the Hellmuth Prize in 2002, and Fellow of the Royal Society of Canada in 2004.
Chemokines; Inflammatory cell; Serine protease inhibitors