Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biol
Open Access

Graeme Hughes

Publications

• Research Article
  LH Supplementation for Low LH Levels during Antagonist IVF Cycles Improves Live Birth Rates
  Author(s): Dean Conrad, Graeme Hughes and Gavin Sacks Dean Conrad, Graeme Hughes and Gavin Sacks
  
  Introduction: Gonadotropin-releasing hormone (GnRH) antagonist IVF protocols often induce a significant decrease in serum luteinizing hormone (LH) levels that may affect assisted reproductive technology cycle outcomes. However, supplementing all women undergoing antagonist cycles with recombinant LH does not improve clinical outcomes. The aim of this study was to assess the impact of LH supplementation specifically in those who had low intra-cycle LH levels. Methods: In this retrospective cohort study, women undergoing IVF/ICSI antagonist cycles had blood tests for LH, oestradiol and progesterone on day 5 of stimulation and then every 1-2 days until the trigger injection leading to egg collection. One group followed the current standard protocol of no LH supplementation given. The other had LH supplementation in the form of either recombinan.. View More»
  DOI: 10.4172/2375-4508.1000155

  Abstract PDF

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