ISSN: 2165-7548
Frederico Raposo
Portugal
Research Article
Impact and Weight of Trauma Load and Inflammation Load Variables on the Severity and Outcome of Major Trauma Patients
Author(s): António Sousa, José Artur Paiva, Sara Fonseca, Luís Valente, Frederico Raposo, Nuno Neves, Filipe Duarte, João Tiago Guimarães and Luís de Almeida
António Sousa, José Artur Paiva, Sara Fonseca, Luís Valente, Frederico Raposo, Nuno Neves, Filipe Duarte, João Tiago Guimarães and Luís de Almeida
Background: Several conditions related to injury severity (trauma load) and systemic inflammatory response (SIRS) after major trauma could affect the outcome. The aim of this study was to assess the influence in the outcome of variables related to trauma and to systemic inflammation after major trauma.
Materials and Methods: Prospective cohort study involving patients admitted to the trauma room of a level 1 trauma center. Variables related to the trauma load and to the inflammation load were collected in the first six hours after trauma. IL-6 was measured on admission and at 24, 48 and 72 hours. All variables were correlated with negative outcomes, namely ICU admission, ARDS development, MODS development and death. Univariate and multivariate analysis were performed.
Results: Ninety nine patients (aged 31 years;, ISS-29) were enrolled. Regarding trauma load variables, i.. View More»
DOI:
10.4172/2165-7548.1000299