Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Elliot D Rosenstein
Institute for Rheumatic & Autoimmune Diseases, Overlook Medical Center,
33 Overlook Road, Summit, NJ
Tanzania
Research Article
Obstructive Sleep Apnea and Lymphocytic Sialadenitis: The Focus isnt Just Sjgrens Syndrome
Author(s): Ashhad Mahmood, Jonathan F Lara and Elliot D RosensteinAshhad Mahmood, Jonathan F Lara and Elliot D Rosenstein
Objective: We examined the presence of lymphocytic infiltration and measured focus scores in uvular specimens of patients with obstructive sleep apnea (OSA).
Methods: We reviewed the histopathology of 101 uvular specimens obtained from patients with OSA and uvular hypertrophy. A lymphocyte focus score assessment was performed for each case.
Results: Of the 101 cases, 42 (42%) cases had a positive focus score (score ≥ 1). Of those cases with a positive focus score, 22 (52%) had a focus score of 1, 14 (33%) had a focus score of 2, 4 (9%) had a focus score of 3, and 2 (5%) had a focus score of 4. Of the 59 patients (58%) with negative focus scores, 39 (66%) had minor lymphocytic infiltrates; 17 (29%) had features of chronic sialadenitis or extensive fibrosis; 3 (5%) had salivary mucosa without any apparent lymphocyt.. View More»
DOI:
10.4172/2155-9899.1000368