Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biol
Open Access
ISSN: 2375-4508
+44 1478 350008
ISSN: 2375-4508
+44 1478 350008
E Velilla
Paseo Manel Girona 33, 08034 Barcelona
Spain
Research Article
Improvement of Fertilization Rates of In Vitro Cultured Human Embryos by Exposure to Sound Vibrations
Author(s): M López-Teijón, C Castelló, M Asensio, P Fernández, P Fernández, A Farreras, S Rovira, JM Capdevila and E VelillaM López-Teijón, C Castelló, M Asensio, P Fernández, P Fernández, A Farreras, S Rovira, JM Capdevila and E Velilla
Exposure of in vitro cultured human embryos to microvibrations can improve embryo development, but music as a source of mechanical vibrations has not yet been explored. To determine the effect of the exposure to music during in vitro culture, 967 oocytes (114 patients) were analyzed. Before insemination, oocytes from each patient were randomly assigned to two groups: embryo culture exposed to music (479 oocytes), and embryo culture without music (488 oocytes). Three different types of music were also tested: pop, heavy metal and classical. Fertilization rates and embryo quality (score, cleavage stage and multinucleation) were compared using a generalized linear mixed model (two levels were considered) and analyzed by means of Bayesian inferences using Integrated Nested Laplace (INLA). Results showed that fertilization rates were 4.82% higher when oocytes were exposed to music but no s.. View More»
DOI:
10.4172/2375-4508.1000160