Internal Medicine: Open Access
Open Access
ISSN: 2165-8048
ISSN: 2165-8048
Camelia Bud
Romania
Case Report
Methotrexate Therapy in Deep Venous Thrombosis in Behcet Disease in Children
Author(s): Lucia Burac, Genel Sur, Ioan Marian, Tudor Vasile, Sorin Dudea and Camelia BudLucia Burac, Genel Sur, Ioan Marian, Tudor Vasile, Sorin Dudea and Camelia Bud
Behcet disease is a chronic condition, systemic disease, with etiopathology still incomplete known but in witch are involved immune and genetic factors who may lead to inflammation and coagulation conditions. Authors present the case of a patient, masculine sex, 14 years old, diagnosed with Behcet disease, who had the vascular manifestation, with deep and superficial lower extremity vein thrombosis, that appeared at more than five years after first signs of disease (recurrent oral ulcerations). The patient had not presented positive markers for primary thrombophilia. Methotrexate therapy led to complete disappearance of lower extremity vein thrombosis, after about one year of treatment (as shown in Doppler vascular ultrasound). No side effect was observed related to Methotrexate therapy.
Conclusions: Methotrexate therapy may be a very efficient alternative t.. View More»
DOI:
10.4172/2165-8048.1000153