Journal of Thyroid Disorders & Therapy
Open Access
ISSN: 2167-7948
+44 1300 500008
ISSN: 2167-7948
+44 1300 500008
Bu Kyung Kim
Kosin University College of Medicine, Kosin University Gospel Hospital,
Busan
Taiwan
Case Report
Lower Starting Dose of Sorafenib for Thyroid Cancer : A Case Report and Literature Review
Author(s): Eun Mi Lee, Ju Won Lee, Jun Yeob Lee and Bu Kyung KimEun Mi Lee, Ju Won Lee, Jun Yeob Lee and Bu Kyung Kim
Since the FDA approved sorafenib use for thyroid cancer, administration of this medicine to thyroid-cancer patients had steadily increased. However, an appropriate starting dose for this treatment has not been established, which is problematic because the sorafenib discontinuation rate due to toxicity is higher among thyroid cancer patients than among patients with other solid tumors. We recently treated a papillary thyroid cancer patient who experienced a dramatic improvement after being treated with a 400-mg starting dose of sorafenib. Herein, we describe this case and discuss its implications for an appropriate sorafenib starting dose for thyroid cancer.
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DOI:
10.4172/2167-7948.1000196