Journal of Clinical and Cellular Immunology

Journal of Clinical and Cellular Immunology
Open Access

ISSN: 2155-9899

+44 1223 790975

Brigitte Katrin Paap

Brigitte Katrin Paap
Institute of Immunology,
Schillingallee 68, 18057 Rostock

  • Review Article
    Molecular Biomarkers in Multiple Sclerosis
    Author(s): Brigitte Katrin Paap, Michael Hecker, Dirk Koczan and Uwe Klaus ZettlBrigitte Katrin Paap, Michael Hecker, Dirk Koczan and Uwe Klaus Zettl

    Multiple Sclerosis (MS) is a chronic immune-modulated disorder of the central nervous system (CNS) affecting mainly young adults. Due to the complexity and heterogenic etiology of this disease diagnosis, treatment, and estimations concerning the future course of the disease for the individual patient are challenging. To encounter the variability in phenotype, disease progression and response to treatments, various new drugs are in development to complement existing treatment options. Since years intensive efforts are directed to identify biomarkers that are associated with various aspects of MS on different levels of the organizational hierarchy of the human body (e.g. DNA, RNA, proteins, cells). We researched the last ten years of literature to identify those proposed candidates that had been repeatedly published as being associated with MS etiology, clinical manifestation, dis.. View More»
    DOI: 10.4172/2155-9899.S10-009

    Abstract PDF

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