Immunological Disorders and Immunotherapy
Open Access
ISSN: 2593-8509
ISSN: 2593-8509
Alioune Dieye
Senegal
Research Article
Profile of Cytotoxic Tcd8 Cells in Different forms of Malaria in Children
Author(s): Tariam Djibangar Agnès, Romuald Dassé Séry, Kouabla Liliane Siransy, Richard Yé boah Oppong, Adjoumanvoulé Honoré Adou, Sansan Hien, Amah Patricia Victorine Goran-Kouacou, Koffi N’ Guessan, Babacar Mbengue, Alioune Dieye and Sombo Mambo FrançoisTariam Djibangar Agnès, Romuald Dassé Séry, Kouabla Liliane Siransy, Richard Yé boah Oppong, Adjoumanvoulé Honoré Adou, Sansan Hien, Amah Patricia Victorine Goran-Kouacou, Koffi N’ Guessan, Babacar Mbengue, Alioune Dieye and Sombo Mambo François
Introduction: Our study focused on the value of TCD8 cytotoxicity in susceptibility to severe malaria in endemic areas. The global purpose of the work hereby was to evaluate adaptive cellular immunity during Plasmodium falciparum malaria through TCD8+ cytotoxic lymphocytes.
Patients and methods: It was a prospective study, with analytical purpose that took place over a period of 8 months in the Pediatric Department of Hôpital Général d’Abobo and in the Immunology and Hematology Laboratory of CHU de Cocody. The study focused on 50 children (under 15 years of age) selected on the basis of WHO definition criteria for malaria infections (40 children with simple malaria and 10 severe malaria) a fact sheet and 10 witness persons. The samples carried were sent and processed in the said-laboratory.
Results:.. View More»
DOI:
10.35248/2593-8509.17.2.115