GET THE APP

Clinical & Experimental Cardiology

Clinical & Experimental Cardiology
Open Access

ISSN: 2155-9880

+44 1300 500008

Alexander E Berezin

Alexander E Berezin

26, Mayakovsky av, Zaporozhye
Ukraine

Publications
  • Mini Review
    The Role of Circulating Myeloid-Related Protein Complex Calprotectin in Prediction of Heart Failure with Preserved Ejection Fraction
    Author(s): Alexander E BerezinAlexander E Berezin

    Both phenotypes of heart failure (HF) with preserved (HFpEF) and reduced (HFrEF) ejection fraction associate with various co-morbidities. The role of specific mediators in certain pathological conditions related to HFpEF and reduced HFrEF is not completely investigated. In this context, the discovery of novel biomarkers that might predict the development of HFpEF is attractive. The objective of the mini review: to investigate the potential role of calprotectin in identifying patients at higher risk of HFpEF phenotype development. Calprotectin (known as Myeloid- Related Protein complex 8/14, S100A8/A9) is calcium and zinc binding heterocomplex protein that was found in elevated level in several conditions associated with infections, inflammation, autoimmunity, allografts’ rejection, malignancy, obesity/metabolic disorders. In HF individuals calprotectin contributes to maintenance.. View More»
    DOI: 10.4172/2155-9880.1000436

    Abstract PDF

Relevant Topics

Top