Journal of Depression and Anxiety
Open Access

Albert Hofman

Publications

• Research Article
  Depressive Symptoms Prior to and after Incident Cardiovascular Disease and Long-term Survival A population-based Study of Older Persons
  Author(s): Rosanne Freak-Poli, Arfan Ikram M, Oscar H Franco, Albert Hofman and Henning Tiemeier Rosanne Freak-Poli, Arfan Ikram M, Oscar H Franco, Albert Hofman and Henning Tiemeier
  
  Background: Depression after a CVD event is associated with increased mortality. However, little is known about how pre-existing depression affects survival after CVD incidence. Aim: To evaluate whether depressive symptoms measured preceding first incident CVD (pre-CVD), as well as measured after CVD (post-CVD), affect survival. Methods: From the Rotterdam Study, 6,932 persons aged 55+ and free of dementia and CVD completed the Center for Epidemiological Studies Depression (CES-D) scale every 4 to 5 years from 1993. CES-D subdomains were positive affect, negative affect, somatic symptoms and interpersonal affect. Persons were followed for mortality and CVD, defined as incident stroke, heart failure and coronary heart disease (CHD). Results: During 15-year follow-up, 22% of participants su.. View More»
  DOI: 10.4172/2167-1044.1000270

  Abstract PDF

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