Autism-Open Access
Open Access

Abstract

Proteomics and Cholesterol in Autism

Alisa G Woods, Kelly L Wormwood, Armand G Ngounou Wetie, Jeanne P Ryan and Costel C Darie

Autism Spectrum Disorder (ASD) diagnosis is increasing worldwide. ASDs are characterized by impaired social function, stereotyped behaviors/interests and communication deficits. ASD causes are poorly understood and treatments are largely limited to behavioral interventions once problems have developed and been detected. Here we discuss the potential use of mass spectrometry and proteomics in early diagnosis of ASD. The potential link between at least some subtypes of ASD, the cholesterol system and proteins that interact with cholesterol is also discussed.