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Traditionally, closure of ventricular septal defects (VSDs) has been a surgical procedure, however in 1988 Lock et al.  ushered in the era of percutaneous ventricular septal defect closure when they reported on the results of transcatheter VSD closure using the Rashkind double umbrella device in six patients with congenital and acquired VSDs. These investigators also reported on the technique of using an arteriovenous wire loop as part of the closure that is still in use today. Since their initial report, multiple devices other than the Rashkind device have been used to close VSDs including devices that are specifically designed for this purpose. Percutaneous VSD closure has therefore become an acceptable alternative to surgical closure of muscular, traumatic, postoperative residual and post-infarct VSDs. Transcatheter device closure remains controversial for perimembranous VSDs however secondary to the risk of heart block. The purpose of this paper is to report on the current status of percutaneous closure of VSDs.