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Government Medical College and Hospital, India
Posters & Accepted Abstracts: J Clin Exp Dermatol Res
Aim: To study therapeutic efficacy of intralesional tuberculin in the treatment of verruca vulgaris. Material & Method: This was an interventional study. The study population was patients of verruca vulgaris with 10 or less than 10 warts, age <40 years and no other systemic illness. Mantoux test was performed. 40 patients of verruca vulgaris with Mantoux response more than 5 mm were enrolled for the intervention. Each wart was then injected with 0.1 ml of tuberculin at 2 weeks interval for maximum 6 visits. Response in the form of change in size of wart was noted. Side effects like swelling, tenderness, vesiculation were also noted. At least six months of follow up was kept to observe for recurrences, if any. Complete clearance of lesion was taken as complete response. Result was categorized into 4 grades: Grade 0: No response, grade 1: Less than 50% response, grade 2: More than 50 but less than 100% response and grade 3: 100% response. Result: Out of 40 patients, 75% patients showed complete response, 17.5% partial response and 7.5% no response. In grade 0, 1, 2, 3 there were 3 (7.5%), 2 (5%), 5 (12.5%), 30 (75%) patients respectively. 5 out of 40 i.e., 12.5% patients had recurrences. Lesser the number of warts, more are the chances of recurrence (p=0.037). 8 patients showed side effects in the form of blistering and vesiculation. Conclusion: Intralesional tuberculin is an effective therapeutic agent for treatment of warts. No significant association was seen between Mantoux test and complete clearance. Patients with lesser number of lesions have higher chances of recurrences with this mode of therapy. Lesions present in close proximity to each other had shown more side effects.
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