Journal of Clinical and Cellular Immunology
Open Access
ISSN: 2155-9899
ISSN: 2155-9899
Mahdi Ghasemiartiyan
Islamic Azad University, Iran
Posters & Accepted Abstracts: J Clin Cell Immunol
It has been shown that two types of cells (Th1/Th2 cells) play critical roles in defensive immune responses and in immunopathological disorders such as allergic reactions and autoimmune diseases and the methods of detecting Th1 and Th2 cells have become more important. The purpose of this research is to compare the level of Th1 cells (IL-2, IFN-�?�?�?³), Th2 cells (IL-6, IL-10) and serum cortisol hormone in young athlete and non athlete men. This is an applied research that its data is gathered by free method. So in order to carry out the research among healthy and volunteer people, 20 of them (weight: 78�?�?�?±4.1 Kg, height: 179�?�?�?±3.59 ms, age: 26�?�?�?±4.38 BMI: 24�?�?�?±1.51) are sorted in athletes group (scientific group) and 12 of them (weight: 79�?�?�?±4.62 Kg, height: 181�?�?�?±2.51 ms, age: 25�?�?�?±4.32 BMI: 24�?�?�?±1.63) in non athletes group (control group). The scientific group includes that athlete who has at least 6 months of regular aerobic exercise and the control group is the peoples who do not have any sport experience. Blood samples for evaluating the above factors in ELISA method are taken from both groups. Considering that the data were normal, with a T test, the independent student in the meaningful level of (P�?¢�?�?�?¤0/005) is examined. Comparing the average amount of IL-2, IL-6, IL-10, IFN-�?�?�?³ and serum Cortisol hormone in both groups, the amount of IL-6 and cortisol hormones in the scientific group has reduced considerably (p<0/05). The results of this research showed that aerobic exercise changed the balance of Th1/Th2 to TH1; this change is an effect of the reduction of TH1 anti-inflammatory cytokines and can be helpful in cure of rheumatic and allergic sickness.