Socio-demographic and exposure factors associated with confirmed | 58519
Journal of Clinical and Cellular Immunology

Journal of Clinical and Cellular Immunology
Open Access

ISSN: 2155-9899

Socio-demographic and exposure factors associated with confirmed cases of monkeypox infection in Bayelsa State, Nigeria, 2017

3rd International Conference on Influenza Research and Emerging Infectious Diseases

April 10-11, 2019 | Toronto, Canada

Samuel Owoicho

Niger Delta University Teaching Hospital, Nigeria

Posters & Accepted Abstracts: J Clin Cell Immunol

Abstract :

Background: An outbreak of Monkeypox, a rare viral zoonotic disease caused by an Orthopoxvirus, was reported in Bayelsa on September 22, 2017. We investigated the outbreak to characterize the cases and determine associated factors.

Methods: We reviewed hospital records of Yenagoa and Ogbia Local Government Area for suspected or confirmed cases at Niger Delta University Teaching hospital (NDUTH) and extracted data on socio-demography and clinical features. We conducted an unmatched case-control study from September 25 to November 8, 2017. We defined a confirmed case as any person presenting with a history of sudden onset of fever, vesiculopustular rash occurring mostly on the face, palms, and soles of the feet with laboratory confirmation of monkeypox virus (any of a positive IgM antibody, PCR or virus isolation). Controls were healthy family members and neighbors randomly selected. All 10-confirmed cases and 80 controls were recruited. A bivariate analysis was performed to determine associated factors, using Fisher’s exact test, and p<0.05 was considered significant. We also carried out an environmental assessment for the houses of cases.

Results: The median age of the cases was 28.5 years (Range: 6-43 years), while that of the controls was 31 years (Range: 16-68 years). One of the cases committed suicide on admission at NDUTH. About 80% of the cases were male and single. Being single (OR=7.6; 95% CI: 1.4-76.1) and attending churches and burial ceremonies (OR: 0.02; 95% CI: 0.01-0.86) were associated with the risk of developing monkeypox infection. All cases and 26 (86.7%) controls were found to be living in rodentinfested houses.

Conclusion: Being single and attending churches and burial ceremonies were found to be risk factors in acquiring monkeypox. Public awareness on avoidance of body contacts during social gatherings and strict environmental sanitation were recommended.

Biography :



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