Journal of Clinical & Experimental Dermatology Research
Open Access

Re-epitheliazation across ethnic groups with human-like Epidermal Growth Factor (EGF)

4^th International Conference and Expo on Cosmetology & Trichology

June 22-24, 2015 Philadelphia, USA

Vincent Wong

Posters-Accepted Abstracts: J Clin Exp Dermatol Res

Abstract :

Epidermal Growth Factor (EGF) is present in a wide variety of tissues and fluids, and serves primarily in a mitogenic and mobilizing capacity on keratinocytes, fibroblasts and smooth muscle cells. It influences several principal constituents of tissue organization including fibroblastic deposition of collagen and fibronectin. EGF has been widely studied and is known to aid in wound healing and tissue repair by acting through proliferative and migratory effects on most human cells. Three of four major EGF receptors are found in the various strata of the skin; the binding by EGF results in an elaborate cascade of intracellular signals leading to gene expression. As humans naturally age, there is a decrease in the number EGF receptors and their response, contributing to the visible signs of ageing (e.g. wrinkle formation). The severity of this change varies across different ethnic groups. This presentation will explore the efficacy of human-like EGF protein bioengineered from barley on the appearance and texture of skin from different ethnic origins and the possible combination with existing treatments to enhance the cosmetic results.