Journal of Clinical & Experimental Dermatology Research
Open Access

Prevalence of liver dysfunction and its related factors in psoriasis patients referred to Imam Khomeini Hospital from 2014-2015

International Conference on Psoriasis and Skin Specialists Meeting

December 08-09, 2016 Dallas, USA

Parvin Mansouri, Zahra Azizian, Reza Chalangari and Katalin Martits Chalangari

Tehran University of Medical Sciences, Iran
Iran University of Medical Sciences, Iran
Mona Lisa Dermatology, USA

Scientific Tracks Abstracts: J Clin Exp Dermatol Res

Abstract :

Introduction: Psoriasis is an inflammatory disease of the skin. Most studies have shown a higher prevalence of metabolic syndrome (MS) in psoriatic patients. Recent studies show that liver disease especially non-alcoholic fatty liver disease (NAFLD) is also frequent in psoriasis patients. Aim & Method: We performed a case study on 200 adult psoriasis patients. Liver dysfunction was diagnosed by elevated liver enzymes after excluding other liver diseases. Results: The occurrence of liver enzyme dysfunction was higher in psoriasis patients than in controls (19 patients; P=0.002). Alcohol and smocking has relation with liver dysfunction (P value=0.004) and also liver dysfunction has relation with drugs therapy in psoriasis patients (P value=0.034). Conclusion: Patients with liver dysfunction and psoriasis have more severe skin disease and are at higher risk of severe liver fibrosis than patients without psoriasis. Routine work-up for liver dysfunction may be warranted in patients with psoriasis, especially when potentially hepatotoxic drug therapy is being considered.

Biography :

Parvin Mansouri is currently working as a Professor of Dermatology in Tehran University of Medical Sciences, Iran.

Email: mansouripr@yahoo.com