Journal of Clinical and Cellular Immunology
Open Access

IL-21 and related diseases

2^nd International Conference on Clinical & Cellular Immunology

October 15-17, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Guangjie Chen and Xiaoyin Niu

Accepted Abstracts: J Clin Cell Immunol

Abstract :

IL-21, which is produced by activated NKT cells and CD4 + T cells, exhibits pleiotropic effects not only on a variety of immune cells but also on non-immune cells. It has been demonstrated that IL-21 plays significant roles in the process of autoimmune diseases, inflammatory diseases and cancers. This review intends to give the reader an overview of this cytokine and the relationships between IL-21 and the related diseases of different body systems.