Reproductive System & Sexual Disorders: Current Research
Open Access
ISSN: 2161-038X
ISSN: 2161-038X
Aisha M Elbareg
Misurata University, Libya
Posters & Accepted Abstracts: Reprod Syst Sex Disord
Objectives: To evaluate efficacy and safety of intervention through HTCRS in improvement of pregnancy outcomes in women with history of infertility, recurrent miscarriages (RM) or premature birth. Materials & Methods: A retrospective descriptive study was conducted on 210 patients who underwent HTCRS from March 2012, through January 2015. The patients aged from 24 to 39 years: 162 with primary infertility, 34 with secondary infertility and 14 with histories of RM (>2). The procedures were performed within 3��?5 days after the end of menstruation under laparoscopic supervision. Follow-up hysterosalpingogram (HSG) and hysteroscopy after three months, if inadequate resection, surgery repeated. Moist exposed burn ointment used in prevention of de novo intrauterine adhesions. Reproductive outcomes and early or late complications within one year after surgery were evaluated. Statistical analysis performed using SPSS packages for Windows. P-value was to be significant if <0.05. Results: Septum completely removed during first time HTCRS in 198 patients, 12 patients required additional intervention. Neither immediate nor late complications were encountered. 32 (15.2%) patients lost in follow up. Out of 178 patients, pregnancy achieved in 139 (78.08%): 74 (53.23%) naturally, 21 (15.10%) after IUI and 44 (31.65%) following ART. Patients ended in miscarriages; 27 (19.4%): 14 (31.81%) post ART, 4 (19.04%) after IUI and in 9 (12.16%) women conceived spontaneously. 103 (74.10%) infants born at term, 9 (6.47%) born premature. No ectopic pregnancies recorded. Postoperative rates of miscarriage and preterm labour reduced as compared to before (P<0.0004 and P<0.0011), respectively. No significant difference between age, BMI, infertility type and duration. Conclusion: HTCRS is safe and effective in management of patients with infertility and RM, significantly improving reproductive outcomes by reducing both miscarriage rate and preterm labor and increasing term delivery.