Medicinal & Aromatic Plants
Open Access
ISSN: 2167-0412
ISSN: 2167-0412
Aroona Chabra, Mahdi Fakhar and Bahman Rahimi-Esboe
Mazandaran University of Medical Sciences, Iran
Tehran University of Medical Sciences, Iran
Posters & Accepted Abstracts: Medicinal Plants
Statement of the Problem: Giardia lamblia is a parasite that causes major infection in humans. There are few therapeutics agents with unpleasant adverse effects available for treating giardiasis. Stachys lavandulifolia with polyphenolic structure considered as an antimicrobial agent. In this study, we evaluated the in vitro inhibitory activity of Stachys lavandulifolia leaves on cysts of G. lamblia. Methodology & Theoretical Orientation: G. lambia cysts were isolated from stool samples by sucrose method. Various concentration of the watery and n-hexane extracts of Stachys lavandulifolia leaves (2.5, 5, 10, 25, 50 mg/ml, respectively) were used for giardiacidal activity in six different times (1, 5, 30 min, 1, 3 and 6 hours). Findings: The watery and n-hexane extract revealed great activity compared to the control group (P<0.05). The watery extract at the concentration of 100 mg/ml killed 93% of cysts after 6 hours. The n-hexane extract at the concentration of 100 mg/ml killed 100% of cysts after 6 hours. Both extracts showed time and dose dependent antigiardial activity and the n-hexane extract was better than watery extract. Conclusion & Significance: Stachys lavandulifolia leaves, as a safe herbal medicine could be confirmed for its antigiardial activity.
Aroona Chabra has her passion in improving the health and wellbeing in the way of using herbal medicine base of traditional medicine for treating disease.