Journal of Drug Metabolism & Toxicology

Journal of Drug Metabolism & Toxicology
Open Access

ISSN: 2157-7609


Epidemiology of Mycobacterium tuberculosis infections and antibiotics resistance in Algeria

3rd World Congress and Exhibition on Antibiotics and Antibiotic Resistance

July 31-August 01, 2017 | Milan, Italy

Dalila Benremila and Ferhat Djoudi

University of Bejaia, Algeria

Posters & Accepted Abstracts: J Drug Metab Toxicol

Abstract :

This study was conducted in the ward of control for tuberculosis and respiratory diseases, in Bejaia city. It aimed to, fellow the diagnosis of M. tuberculosis by bacilloscopy and culture in Lowenstein-Jensen medium, to evaluate the impact of some epidemiological factors and finally to test the sensitivity of isolates to antibiotics of first and second line. 104 patients were diagnosed positive for tuberculosis on a total of 707 patients. Patients between 16 to 65 years were the most affected, with 94 of cases, followed by those aged over 65 years with 9 cases. Within children under 15, only one case was recorded. 157 patients supported by the ward were followed in this study. Men represented 52.87% of the total patients. The pulmonary tuberculosis was slightly more frequent than extra pulmonary. 131patients aged between 15 years and 65 years, 19 more than 65 and 7 young patients (less than 15 years). Finally, one case of failure, one of a progressive recovery and one relapse were recorded. Within the 34 isolates tested for drug susceptibility, 13 (38.28%) were resistant, at least, to one antibiotic. The isoniazid is most affected by this resistance, with 9 strains (26.47%), followed by rifampicin, with 3 strains (8.82%). However, only 2 isolates expressed resistance to pyrazinamide (5.88%), one isolate resistant to Streptomycin and another to ethambutol (2.94%).

Biography :