Journal of Clinical & Experimental Dermatology Research
Open Access
ISSN: 2155-9554
ISSN: 2155-9554
Iffat Zareen Ahmad
Integral University, India
Posters & Accepted Abstracts: J Clin Exp Dermatol Res
Chronic skin conditions are not curable and can be managed using drugs and by paying close attention to your lifestyle. Applications of algae in cosmetics and pharmaceutical industries are rapidly growing because of increasing demands from customers; the reason being the safety and efficacy of novel bioactive substance from natural sources than artificial substances. Cyanobacteria are regarded as a potential candidate for this as antibacterial, antiviral, antifungal, algicide and cytotoxic activities have been reported in these organisms. Radiations in the UV-B range have deleterious effects on humans as they generate free radicals and active oxygen species. These deleterious compounds are inactivated by antioxidants. Among them are the carotenoids and phycocyanin which protect against photodynamic action in different ways. Stress plays an important role in the production of bioactive metabolites from organisms. Nostoc muscorum was studied for antibacterial activity against various pathogenic bacteria resistant to a number of available antibiotics after being exposed to UV-B radiation. The antibacterial activity of Nostoc muscorum was studied on five potent skin pathogens. The highest antibacterial activity was seen the methanol extracts of 24 h UV-B exposed cultures of N. muscorum. It can be concluded that there was potent antibacterial activity. Results showed stress, solvent and dose dependent activity. This antibacterial activity might be due to the enhanced synthesis of carotenoids and phycocyanin under UV-B stress. The purpose of the present study was to relate the inhibitory effects of the cyanobacterial compounds specifically on skin pathogens with exposure to UV-B radiation as UV protecting compounds are already reported in these organisms.
Email: iffat@iul.ac.in