Medicinal & Aromatic Plants
Open Access

Development of an anti-aging gel with natural products: hydro-alcholic extracts and essential oils of two species of Salvia ssp

5^th International Conference & Exhibition on Herbal & Traditional Medicine

November 05-06, 2018 | London, UK

Goes Hugo, Meireles Estela, Pereira Olivia, Fernandes Conceicao, Sousa M Joao and Pedro Luis

Instituto Politecnico de Braganca, Portugal
Faculdade de Ciencias da Universidade de Lisboa, Portugal

Posters & Accepted Abstracts: Med Aromat Plants

Abstract :

Salvia officinalis L. and Salvia elegans are perennial plants belonging to Lamiaceae family. New reviews are highlighted pharmacological results attributed to S. officinalis, including anticancer,anti-inflammatory, antioxidant, antimicrobial, antimutagenic, antidementia, hypoglycemic,and hypolipidemic effects. The phytochemicals reported from S. officinalis have been isolated from its essential oil, and infusion preparation. More than 120 components have been characterized in the essential oil of S. officinalis (Ghorbani Esmaeilizadeh, 2017). The objective of this study was to create two anti-ageing gels (Carbopol and Methylcellulose) using essential oil of S. officinalis and hydroalcoholic extracts of S. officinalis and S. elegans. The essential oil was use as preservative and the hydroalcoholic extracts was the bioactive compounds, since it is rich in phenolic compounds with antioxidant capacity. These formulas were put through several tests: stability, physic/chemical, and acute toxicity evaluations. The toxicity test was established using Daphnia magna with objective of LC50 determination after 12 hours. Young daphnids are exposed to a range of concentrations of oil extracts, as well as hydroalcoholic extracts. For S. officinalis five oil concentrations were tested (0.15% to 2.50%) and for S. officinalis and S. ellegans three hydroalcoholic extracts concentrations were tested (1.25%, 2.5%, 5%). Considering S. officinalis, results suggest a decrease toxicity with time exposition, probably due to light or/and oxygen. Considering hydroalcoholic extracts, values of LC50 obtained suggest that, although same pattern, S. ellegans exhibit lower toxicity comparing S. officinalis. Finally, results of Stability Test showed that all samples keep their original properties.

Biography :

Hugo Goes will completed his degree this year in Instituto Politecnico de Bragança and will starte the Master studies in the Pharmacology and chemistry of natural prodouts in Instituto Politecnico de Bragança and Salamanca University. He has published more than 15 posters and comunications in several congress and scientific meetings.

E-mail: joaos@ipb.pt