Comparison of high-risk HPV infection characteristics in women fr | 8103
Journal of Antivirals & Antiretrovirals

Journal of Antivirals & Antiretrovirals
Open Access

ISSN: 1948-5964

+44 1300 500008

Comparison of high-risk HPV infection characteristics in women from two Croatian counties

International conference on Human Papillomavirus

October 20-21, 2016 Chicago, USA

Jasmina Vranes

Zagreb University, Croatia

Scientific Tracks Abstracts: J Antivir Antiretrovir

Abstract :

The aim of this study was to compare the prevalence of high-risk HPV (hrHPV) infection between women from two biggest Croatian counties: The City of Zagreb (CZ) and the Split-Dalmatia County (SDC), considering their age, severity of cervical lesions and distribution of the most important hrHPV types. The study included all women, who were during the eight-month period on their Gynecologist's request, tested on hrHPV infection with molecular cobas HPV Test. The examinees were divided in two age groups (<30 years and â�?¥30 years). No significant difference was determined in the overall prevalence of hrHPV infection between the two counties. Among 3542 cervical swabs analyzed in the CZ, 39.7% was hrHPV positive, while in the SDC the positivity rate among 1594 tested samples was 36.2%. While in the population of women aged â�?¥30 years no significant difference in hrHPV prevalence between two counties was observed (CZ 32.9%, SDC 34.7%), in younger women the difference in prevalence was statistically significant (CZ 52.8%, SDC 39.1%; p<0.01). Analyzing the population of hrHPV positive women, the highest prevalence of HPV16 was observed. In the CZ, further analysis showed that genotype 51 was the second most prevalent HPV type in younger women (HPV16 32% and HPV51 27%), associated with low grade cervical abnormalities. The presence of HPV16 and HPV18 in cervical samples significantly increased with the severity of cervical lesions. Significant epidemiological differences of hrHPV infection in population of adolescent and young women in two studied regions were detected.

Biography :

Jasmina Vranes has completed her PhD from Zagreb University, School of Medicine. She is the Head of Clinical Microbiology Department at Zagreb Institute of Public Health, Croatia and Professor at Zagreb University, Medical School, specialized in Clinical Microbiology and Pediatrics. She has published more than 80 papers in reputed journals and has been serving as an Editorial Board Member of several medical journals. She is a Member of several professional associations such as: Croatian Medical Association, International Society for Infectious Diseases, European Society for Clinical Microbiology and Infectious Diseases etc.